Before a recipient can be matched with an egg donor, the following tests must be carried out:
|Blood Type||Semen Analysis|
|Baseline scan or HSG||Blood Type|
|TSH, T3, T4|
|CBC (Complete Blood Count)|
|Urea, SGOT, SGPT|
NB: These tests must be less than 6 months old at the time of treatment.
You complete a donor characteristic form in which we document the characteristics you would like the donor to have. We use this information to supply you with a list of donors that match your criteria and blood groups. You select your first choice and a reserve donor. This will allow flexibility and avoids delays in case the first choice donor does not produce enough number of eggs or for any reason, decides to withdraw from the programme.
We will provide you with information on:
- Hair colour
- Body build
- Eye Colour
- Number of children of their own if applicable
- Country of origin (ethnicity)
There are two drug regimens
Patients who are menopausal (ie with no periods) Progynova or Estrofem is given for 10-12 days to thicken the uterus lining (endometrium). An ultrasound scan will be performed to check the endometrial thickness. Progesterone support will commence 3-4 days before the embryo transfer.
Patients with naturally occurring periods (ie not thought to be menopausal). In order to control your cycle, you will first need to take oral contraceptive before starting with oral Progynova to thicken the lining of the uterus and progesterone support as above.
In order to sychronise both recipient and donor cycles for fresh embryo transfer it is essential to “switch off” the recipients cycle using a long protocol. The recipient will need to take Nafarelin (Synarel) nasal spray daily, from day 2 or 21 of the menstrual cycle, until the day before the donors egg collection. The endometrium is prepared by giving oral Progynova or Estrofem and progesterone support as above.
For both sets of clients , the drug regime is continued until a pregnancy test is performed.
The success achieved from treatment with egg donation is generally an in vitro fertilization (IVF) application that achieves a success rate of 70% although the treatment differs according to the uterus and internal development of the treated patient and the sperm quality of the partner.
For egg donation, the patient receives a pre-treatment which can vary from 10-15 days before coming to Cyprus. The duration of the treatment is 5 to 7 days depending on the condition of the patient.
Since embryos are evaluated as one-to-one chromosomes in screening with PGT applied together with IVF treatment, 99.9% correct result is obtained. Therefore gender can be guaranteed in gestation to be achieved.
The age of the patient, egg reserve, egg quality, sperm quality, embryo development, number and quality of embryos obtained in the desired gender, uterine wall thickness are the main factors which affect the success.
If the pregnancy does not occur as a result of blood analysis after 12 days of transfer, consult your doctor and the drugs you are using will be stopped and normal menstrual bleeding is expected.
We think it is appropriate to pass at least 2 months between the two in-vitro fertilization treatments both psychologically and in hormonal terms.
After you get positive results from the pregnancy test, be sure to tell your doctor about the result. Continue with the medication you are using as recommended by your doctor.
How long egg collection takes depends on the number of follicles in the ovaries. However it takes 15-30 minutes on average. We recommend that you reserve at least 3 hours for the procedure if the preparations before the procedure and the rest process after the procedure are considered.
You can return to normal life two days after the embryo transfer. If your work is very stressful and tiring, we recommend you to consult your doctor.
After embryo transfer procedure (ET), you should not be sexually active for 12 days until the end of the pregnancy test.
At our center, we have our patients rested in our center for 2 hours after embryo transfer. We recommend you to rest for a day or two after the transfer. There is no damage of plane or car journey 1 day after operation.
You can get a warm shower after a day of embryo transfer. We advise you to avoid hot bath.
The sperm can not be obtained from the root cell yet. Immature sperm cells were matured in the laboratory to obtain pregnancy, but with this method very few pregnancies could be obtained in the world.
Currently, micro-TESE procedure is applied as the last hope for patients with azoospermic disease. If spermatids are obtained as a result of micro-TESE, fertilization can be done by microinjection and the family can have children of their genetic structure. Sperm donation or sperm bank treatments may be given as an option only if the sperm can not be obtained despite micro-TESE procedure.
In normal gestation or in vitro fertilization, fertility is considered to decrease with age. As 20 and 30-year-old women have a chance of 25-30% pregnancy in a one-month cycle under natural conditions, this decreases to 5% at the beginning of their 40s. Age is the most important factor affecting the success rate in fertility treatment. Reasons for this: With the increasing age, the number of eggs in female decreases and their quality deteriorates. In order to control the fertility level of the woman, blood tests can be done on the third day of the menstruation and the amount of FSH, LH, E2 and AMH hormones can be examined. In addition, ultrasonography can be used to evaluate the woman’s ovarian capacity.