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CGT Genetic Carrier Test – Personal Genetic Screening Test


What is CGT Genetic Carrier Test?

Genetic diseases cannot be cured, but they can be prevented.

With the CGT test, it is a test that allows screening of more than 300 genetically transmitted diseases and over 1,600 disease-causing mutations (genetic code disorder) at once.

It is possible to screen and evaluate more than 300 genetically transmitted diseases and more than 1600 disease-causing mutations (genetic code disorder) in a simple blood sample taken from the individual who is planned to be tested with the CGT test.


How is the CGT Genetic Carrier Test Performed?

CGT Genetic Carrier Test

Who Is CGT Gene Screening Recommended For?

It can be applied to any couple requesting the CGT test. However, our patients that we especially recommend to be applied:

  • Akraba evliliği yapanlar,
  • Couples with a family history of carrying a genetic disease,
  • Couples who have given birth to a child with a genetic disease and want to have children again.

The CGT test is also used in egg donation treatments to determine the physical characteristics of egg donors, as well as their general health status and genetic diseases they may carry. In this way, the concerns of the families about the health status of the donor are resolved.


Egg Donation and CGT Gene Screening

Many in vitro fertilization centers serving in Cyprus perform genetic screening tests (Karyotype analysis, Sickle cell, Cystic fibrosis and Thalassemia) to egg donors within the framework of European standards in terms of common genetic diseases and mandated by the TRNC Ministry of Health. These tests, although genetic screening tests are very limited.

Today, there are hundreds of genetic diseases that couples or donors receiving treatment can carry without realizing it, and unfortunately, it was not possible medically and technically to screen for these genetic diseases until recently. The most frequently asked questions from couples undergoing treatment are; How healthy is the egg we receive, can an unknown genetic disease be transmitted from the donor to our child, how well are egg donors examined in terms of possible genetic diseases.

Known as Dogus IVF Center, we can prevent disease transmission by applying CGT test to donors for more than 300 genetic diseases.


CGT Gene Screened Donor Selection and Egg Donation Treatment

As the first step of the treatment, it is learned what kind of donor the family wants. Later, the father-to-be comes to our center and gives a sperm sample. The sperm sample taken is frozen and the donor’s CGT test result is expected to be concluded.

After the selection from the donor pool for the CGT test, a blood sample is taken from the donor you selected and sent to the genetic center and you are informed according to the result. The examination of the CGT test takes approximately 2-4 weeks.

With the positive result, your donor is taken to egg multiplication treatment and all the eggs obtained are fertilized with the sperm waiting in our center as frozen beforehand, and the embryos are packed in 5 days and frozen.


CGT Gene Screening and IVF Approach in Consanguineous Marriages

Among the countries including Turkey, consanguineous marriages are frequently encountered. The CGT test is of great importance as these couples are more likely to have children with genetic diseases. Thanks to this test, genetic selection can be applied to ensure that couples give birth to healthy babies, even in consanguineous marriages.


Screening of Couples Who Will Have IVF

In consanguineous marriages, similar mutations in the mother and father can cause disease in the child. Carrier tests for couples in this situation will reduce the risk of possible genetic diseases that they may be carrying and that can be passed on to their children.


Determination of Mutation with CGT Test Result

If any disease carrier or mutation is detected after the personalized genetic screening test before pregnancy, this mutation can be screened in embryos with PGD method during the in vitro fertilization process, and it is possible to have a healthy child without the disease by transferring embryos that do not carry mutations.

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